Senior Scientist - In Vitro Pharmacology

Job Ref: J27569
Sector: Science
Sub-sector: Biotech/Life Sciences
Job Type: Permanent
Date Added: 10 July 2018
  • Cambridge, Cambridgeshire, England, UK
  • Competitive
  • Neil Walton
  • 0203 096 4700

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Senior Scientist - In Vitro Pharmacology

Competitive salary, commensurate with experience + Excellent Benefits

Based in Cambridge

Do you have extensive experience of Molecular Phamacology / In Vitro Pharmacology supporting novel drug discovery?

Would you like to work for a cutting edge Pharmaceutical company in Cambridge?

Working in a key laboratory-based role based at a leading Drug Discovery Company located in Cambridge, UK, you will contribute to a number of drug discovery (small molecules & biologics) programs. The company has a unique structure-based approach to discovering therapeutic agents for diseases across a number of therapeutic areas, and relies on a proprietary approach to stabilise receptors enabling their purification for structural and biophysical studies. The company works in collaboration with major global pharmaceutical companies on both small molecule and antibody discovery programmes, and is also developing its own pipeline of novel small molecules and peptides. The most advanced of these is now in Phase I clinical studies with others moving towards clinical development. As a result of the increased activities in building its own pipeline, they now seek to recruit a highly motivated laboratory-based in vitro pharmacologist to join the Molecular Pharmacology team.

As a Senior Scientist you will play a key role in the Molecular Pharmacology team, which is responsible for both new drug target validation and supporting all drug discovery phases up to pre-clinical candidate (PCC) selection including assay development, provision of routine small/large molecule screening and more detailed mechanism of action studies.

To be considered you will need the following experience;

  • A PhD or Postgraduate degree in biochemistry, immunology, cell biology, pharmacology, molecular biology or similar biological sciences
  • Thorough knowledge of experimental design, and a high level of technical laboratory skill gained through substantial doctoral academic / industry background.
  • Prior experience of GPCR pharmacology, supporting drug divcovery.
  • Preferable laboratory techniques include; cell culture/immune cell isolation, GPCR signaling, qPCR technology platforms, flow cytometry and assay automation techniques.

Candidates must be highly motivated, flexible scientists with the ability to multi-task. Good interpersonal skills are also essential as you will be working closely with other members of key drug discovery programmes and with scientists from other disciplines in support of our research projects.

Key Words "GPCR, G Protein Coupled Receptor, Membrane Protein, 7TM, Transmembrane Protein, Drug Discovery, Cell Culture, Liquid Handling, molecular screening, Pharmacology, Cell-Based assay, Pharmacologist, receptor, assay development, ligand binding, binding assay, FLIPR assay, biochemical assay, drug design, molecular pharmacologist, antibody, antibodies"

Please apply online, or call Neil Walton on 02030964706

The recruiter has stated that all applicants for this job should be able to prove they are legally entitled to work in the UK. SRG is a trading name of Science Recruitment Group Ltd an Employment Business/Agency.

09/08/2018 11:39:41